Apr 10, 2018 ... The amide resonance intensity of Y157 from Ras-GTP is known to gradually decline while the corresponding resonance from Ras-GDP ...

www.ncbi.nlm.nih.gov

Mar 19, 2013 ... RAS-GTP-derived peaks eventually shift to GDP positions as hydrolysis occurs ( shown for Y157). (C) Use of peak intensity data to determine ...

www.pnas.org

Directly after protein purification and sample preparation, Y157 peaks representative of both the. GTP and GDP bound conformational states were visible, ...

pdfs.semanticscholar.org

Figure S2, related to Figure 3. Crystal and predicted structures of Ras dimers. (A) Crystal interfaces projected on the GTP-bound Ras homodimer (H-Ras-GTP ...

www.cell.com

Jul 7, 2015 ... ... E143 in β6, and Y157 in α5 regions (Figure 5D; Figure S5B). Although the dilution-induced CSPs in GTP-γ-S-loaded full-length and truncated ...

www.sciencedirect.com

(M1, M67, M72, M111, M182) were oxidized and five tyrosines (Y4, Y40, Y96, Y137, Y157) were nitrated. Cys118, which resides in the GTP binding site, was ...

www.bumc.bu.edu

A web application platform for the interactive exploration of cancer mutations in 3D.

cancer.sanger.ac.uk

(D) I46 and D47 (β 2-β 3) drive Y157 (α 5). from publication: Intrinsic K-Ras dynamics: A novel molecular dynamics data analysis method shows causality ...

www.researchgate.net

Nov 15, 2016 ... S3A,B demonstrate that information flows from β2-β3 to Y157 (α5). These findings improve on the previous observations of Abankwa et al.

www.nature.com

Overlay analysis confirmed the Y157 could function as an SH2 binding site in addition to other potential phosphotyrosine sites, such as Y32 ( Fig. 4 A and B).

www.researchgate.net

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